B. Upton
TB
Homeruns
| Game Date | Season # | Opp. | Pitcher | Inning | B | S | O | Runners | Com. |
| September 12th | 24 | Bos | Lester | 1 | 0 | 0 | 1 | 1 | 0 |
| September 8th | 23 | Tor | Accardo | 9 | 0 | 0 | 2 | 1 | 0 |
| September 1st | 22 | NYY | Kennedy | 6 | 2 | 1 | 1 | 0 | 0 |
| August 30th | 21 | Bal | Guthrie | 3 | 0 | 1 | 2 | 2 | 0 |
| August 26th | 20 | Oak | Haren | 2 | 2 | 1 | 0 | 0 | 0 |
| August 24th | 19 | Oak | Casilla | 6 | 0 | 1 | 1 | 1 | 0 |
| August 22nd | 18 | Bos | Matsuzaka | 6 | 1 | 0 | 1 | 1 | 0 |
| August 19th | 17 | Cle | Sabathia | 4 | 3 | 2 | 2 | 0 | 0 |
| August 6th | 16 | Det | Verlander | 5 | 0 | 0 | 1 | 2 | 0 |
| August 5th | 15 | Bal | Bedard | 3 | 0 | 0 | 1 | 1 | 0 |
| July 30th | 14 | Tor | Janssen | 8 | 2 | 1 | 2 | 0 | 0 |
| July 29th | 13 | Bos | Delcarmen | 7 | 0 | 0 | 2 | 2 | 0 |
| July 21st | 12 | NYY | Igawa | 1 | 2 | 1 | 2 | 0 | 0 |
| July 20th | 11 | NYY | Proctor | 9 | 1 | 0 | 0 | 0 | 0 |
| July 20th | 10 | NYY | Mussina | 3 | 0 | 0 | 1 | 1 | 0 |
| June 5th | 9 | Tor | Halladay | 4 | 3 | 0 | 1 | 1 | 0 |
| September 26th | 9 | Det | Seay | 7 | 0 | 1 | 1 | 0 | 0 |
| May 23rd | 8 | Sea | Batista | 1 | 0 | 1 | 0 | 0 | 0 |
| August 17th | 8 | Tex | Nippert | 4 | 2 | 1 | 2 | 1 | 0 |
| May 10th | 7 | Bal | Cabrera | 5 | 3 | 1 | 2 | 0 | 0 |
| August 3rd | 7 | Det | Farnsworth | 8 | 3 | 1 | 1 | 1 | 0 |
| May 6th | 6 | Oak | Blanton | 2 | 3 | 1 | 0 | 0 | 0 |
| June 30th | 6 | Bos | Masterson | 1 | 0 | 0 | 0 | 0 | 0 |
| April 29th | 5 | Oak | Braden | 4 | 0 | 0 | 1 | 2 | 0 |
| June 8th | 5 | Tex | Mathis | 6 | 3 | 2 | 1 | 1 | 0 |
| April 28th | 4 | Oak | Haren | 2 | 1 | 0 | 2 | 0 | 0 |
| June 6th | 4 | Tex | Padilla | 6 | 0 | 1 | 2 | 0 | 0 |
| October 18th | 4 | Bos | Beckett | 1 | 3 | 2 | 1 | 0 | 0 |
| April 23rd | 3 | NYY | Igawa | 4 | 2 | 2 | 1 | 0 | 0 |
| April 29th | 3 | Bal | Bierd | 7 | 3 | 2 | 2 | 1 | 0 |
| October 16th | 3 | Bos | Matsuzaka | 1 | 1 | 1 | 0 | 1 | 0 |
| April 20th | 2 | Cle | Sabathia | 3 | 0 | 0 | 2 | 0 | 0 |
| April 14th | 2 | NYY | Bruney | 7 | 0 | 2 | 1 | 1 | 0 |
| October 6th | 2 | CWS | Floyd | 3 | 3 | 2 | 1 | 0 | 0 |
| October 13th | 2 | Bos | Lester | 3 | 2 | 1 | 0 | 2 | 0 |
| April 6th | 1 | Tor | Chacin | 3 | 1 | 0 | 1 | 0 | 0 |
| April 13th | 1 | Bal | Burres | 5 | 3 | 2 | 2 | 2 | 0 |
| October 6th | 1 | CWS | Floyd | 1 | 2 | 1 | 1 | 0 | 0 |
| October 11th | 1 | Bos | Beckett | 3 | 2 | 0 | 1 | 0 | 0 |