D. Ortiz
Bos
Homeruns
| Game Date | Season # | Opp. | Pitcher | Inning | B | S | O | Runners | Com. |
| September 28th | 35 | Min | Guerrier | 8 | 1 | 0 | 1 | 0 | 0 |
| September 27th | 34 | Min | Bonser | 5 | 1 | 1 | 0 | 0 | 0 |
| September 25th | 33 | Oak | Meyer | 8 | 1 | 2 | 1 | 1 | 0 |
| September 21st | 32 | TB | Ridgway | 9 | 1 | 1 | 0 | 2 | 0 |
| September 12th | 31 | TB | Reyes | 9 | 3 | 1 | 1 | 1 | 0 |
| September 12th | 30 | TB | Jackson | 3 | 0 | 1 | 0 | 2 | 0 |
| September 11th | 29 | TB | Salas | 7 | 0 | 0 | 0 | 0 | 0 |
| September 8th | 28 | Bal | Leicester | 1 | 1 | 0 | 1 | 1 | 0 |
| September 6th | 27 | Bal | Cherry | 5 | 3 | 2 | 1 | 0 | 0 |
| August 31st | 26 | Bal | Liz | 1 | 1 | 1 | 2 | 0 | 0 |
| August 29th | 25 | NYY | Clemens | 6 | 1 | 0 | 1 | 0 | 0 |
| August 26th | 24 | CWS | Vazquez | 5 | 0 | 0 | 2 | 1 | 0 |
| August 24th | 23 | CWS | Floyd | 5 | 0 | 0 | 0 | 0 | 0 |
| September 22nd | 23 | Cle | Jackson | 5 | 2 | 1 | 2 | 0 | 0 |
| August 24th | 22 | CWS | Danks | 4 | 0 | 0 | 0 | 1 | 0 |
| September 21st | 22 | Tor | Richmond | 3 | 3 | 2 | 2 | 1 | 0 |
| August 18th | 21 | LAA | Weaver | 5 | 0 | 0 | 0 | 3 | 0 |
| September 17th | 21 | TB | Garza | 4 | 2 | 0 | 0 | 0 | 0 |
| August 17th | 20 | LAA | Lackey | 1 | 2 | 2 | 1 | 1 | 0 |
| September 17th | 20 | TB | Garza | 1 | 1 | 1 | 1 | 1 | 0 |
| August 3rd | 19 | Sea | Ramirez | 3 | 1 | 1 | 0 | 0 | 0 |
| September 15th | 19 | TB | Kazmir | 1 | 1 | 1 | 0 | 2 | 0 |
| July 31st | 18 | Bal | Bell | 8 | 1 | 1 | 0 | 0 | 0 |
| September 7th | 18 | Tex | McCarthy | 5 | 2 | 2 | 2 | 1 | 0 |
| July 31st | 17 | Bal | Bedard | 3 | 0 | 0 | 2 | 1 | 0 |
| August 14th | 17 | Tex | Hunter | 2 | 1 | 0 | 2 | 2 | 0 |
| July 16th | 16 | KC | Bannister | 6 | 3 | 2 | 1 | 1 | 0 |
| July 14th | 15 | Tor | McGowan | 1 | 3 | 0 | 2 | 0 | 0 |
| August 12th | 15 | Tex | Feldman | 1 | 0 | 0 | 2 | 2 | 0 |
| July 7th | 14 | Det | Bonderman | 1 | 2 | 1 | 1 | 1 | 0 |
| July 27th | 14 | NYY | Ponson | 4 | 3 | 2 | 2 | 1 | 0 |
| June 20th | 13 | Atl | Carlyle | 2 | 1 | 1 | 2 | 1 | 0 |
| May 31st | 13 | Bal | Olson | 3 | 1 | 1 | 2 | 0 | 0 |
| June 19th | 12 | Atl | Hudson | 4 | 3 | 1 | 2 | 0 | 0 |
| May 26th | 12 | Sea | Hernandez | 4 | 1 | 0 | 2 | 0 | 0 |
| June 7th | 11 | Oak | Blanton | 1 | 3 | 2 | 2 | 0 | 0 |
| May 25th | 11 | Oak | Blanton | 1 | 0 | 1 | 2 | 0 | 0 |
| June 4th | 10 | Oak | Haren | 1 | 3 | 2 | 2 | 0 | 0 |
| May 18th | 10 | Mil | DiFelice | 5 | 2 | 2 | 0 | 1 | 0 |
| May 9th | 9 | Tor | Towers | 8 | 3 | 2 | 2 | 1 | 0 |
| May 18th | 9 | Mil | Villanueva | 3 | 2 | 2 | 2 | 0 | 0 |
| May 4th | 8 | Min | Silva | 6 | 1 | 1 | 1 | 0 | 0 |
| May 17th | 8 | Mil | Suppan | 2 | 3 | 2 | 2 | 2 | 0 |
| April 29th | 7 | NYY | Wang | 1 | 0 | 0 | 2 | 0 | 0 |
| May 6th | 7 | Det | Robertson | 7 | 3 | 2 | 1 | 0 | 0 |
| April 21st | 6 | NYY | Karstens | 4 | 1 | 1 | 2 | 1 | 0 |
| May 5th | 6 | Det | Jones | 9 | 3 | 1 | 1 | 0 | 0 |
| April 18th | 5 | Sea | Ohka | 7 | 1 | 0 | 0 | 0 | 0 |
| April 30th | 5 | Tor | McGowan | 7 | 2 | 0 | 1 | 0 | 0 |
| April 16th | 4 | LAA | Santana | 4 | 1 | 0 | 2 | 0 | 0 |
| April 24th | 4 | LAA | Shields | 9 | 2 | 2 | 2 | 1 | 0 |
| April 14th | 3 | LAA | Jones | 8 | 2 | 1 | 0 | 2 | 0 |
| October 16th | 3 | Cle | Byrd | 6 | 2 | 1 | 0 | 0 | 0 |
| April 23rd | 3 | LAA | Garland | 5 | 0 | 0 | 1 | 1 | 0 |
| April 8th | 2 | Tex | Padilla | 3 | 2 | 1 | 2 | 1 | 0 |
| April 18th | 2 | Tex | Mendoza | 3 | 0 | 0 | 2 | 3 | 0 |
| April 8th | 1 | Tex | Padilla | 1 | 2 | 1 | 2 | 0 | 0 |
| October 3rd | 1 | LAA | Lackey | 3 | 1 | 0 | 1 | 1 | 0 |
| October 7th | 1 | LAA | Weaver | 4 | 0 | 1 | 0 | 0 | 0 |
| April 2nd | 1 | Oak | Embree | 7 | 0 | 1 | 0 | 1 | 0 |