J. Thome
CWS
Homeruns
| Game Date | Season # | Opp. | Pitcher | Inning | B | S | O | Runners | Com. |
| September 29th | 35 | Det | Verlander | 1 | 0 | 0 | 1 | 1 | 0 |
| September 28th | 34 | Det | Vasquez | 7 | 0 | 1 | 1 | 0 | 0 |
| September 30th | 34 | Min | Blackburn | 7 | 2 | 2 | 0 | 0 | 0 |
| September 26th | 33 | KC | Greinke | 1 | 0 | 0 | 2 | 0 | 0 |
| September 19th | 33 | KC | Bannister | 5 | 0 | 1 | 1 | 0 | 0 |
| September 22nd | 32 | Min | Bonser | 3 | 2 | 0 | 0 | 0 | 0 |
| September 14th | 32 | Det | Rogers | 4 | 3 | 2 | 0 | 0 | 0 |
| September 21st | 31 | Min | Santana | 5 | 0 | 1 | 2 | 2 | 0 |
| September 11th | 31 | Tor | Downs | 8 | 1 | 1 | 2 | 1 | 0 |
| September 19th | 30 | KC | Bannister | 5 | 1 | 2 | 0 | 0 | 0 |
| September 6th | 30 | LAA | Speier | 15 | 0 | 1 | 1 | 0 | 0 |
| September 19th | 29 | KC | Bannister | 3 | 0 | 0 | 1 | 0 | 0 |
| August 31st | 29 | Bos | Wakefield | 1 | 1 | 1 | 2 | 1 | 0 |
| September 16th | 28 | LAA | Moseley | 9 | 3 | 2 | 0 | 1 | 0 |
| August 25th | 28 | Bal | Waters | 6 | 0 | 1 | 1 | 0 | 0 |
| September 12th | 27 | Cle | Westbrook | 4 | 2 | 0 | 0 | 0 | 0 |
| August 24th | 27 | TB | Sonnanstine | 4 | 0 | 1 | 0 | 1 | 0 |
| September 9th | 26 | Min | Rincon | 8 | 2 | 0 | 1 | 0 | 0 |
| August 19th | 26 | Sea | Hernandez | 5 | 1 | 1 | 0 | 0 | 0 |
| September 8th | 25 | Min | Garza | 1 | 2 | 0 | 2 | 0 | 0 |
| August 14th | 25 | KC | Peralta | 6 | 3 | 1 | 2 | 2 | 0 |
| September 7th | 24 | Min | DePaula | 9 | 0 | 1 | 0 | 2 | 0 |
| August 10th | 24 | Bos | Buchholz | 3 | 0 | 0 | 1 | 1 | 0 |
| August 30th | 23 | Tex | Millwood | 1 | 0 | 1 | 2 | 0 | 0 |
| August 9th | 23 | Bos | Timlin | 9 | 1 | 1 | 2 | 0 | 0 |
| August 28th | 22 | Tex | Gabbard | 3 | 0 | 0 | 1 | 0 | 0 |
| August 6th | 22 | Det | Verlander | 1 | 0 | 1 | 2 | 2 | 0 |
| August 21st | 21 | KC | Nunez | 3 | 1 | 1 | 1 | 1 | 0 |
| August 2nd | 21 | KC | Davies | 2 | 1 | 0 | 0 | 0 | 0 |
| August 18th | 20 | Sea | Sherrill | 8 | 2 | 0 | 2 | 1 | 0 |
| July 31st | 20 | Min | Baker | 2 | 3 | 2 | 0 | 1 | 0 |
| August 18th | 19 | Sea | Weaver | 1 | 3 | 2 | 2 | 0 | 0 |
| July 23rd | 19 | Tex | Millwood | 1 | 1 | 0 | 2 | 2 | 0 |
| August 4th | 18 | Det | Bonderman | 3 | 1 | 0 | 1 | 0 | 0 |
| July 12th | 18 | Tex | Loe | 8 | 3 | 2 | 1 | 1 | 0 |
| July 24th | 17 | Det | Durbin | 7 | 3 | 0 | 2 | 2 | 0 |
| July 11th | 17 | Tex | Rupe | 7 | 3 | 2 | 2 | 0 | 0 |
| July 20th | 16 | Bos | Beckett | 3 | 3 | 2 | 1 | 2 | 0 |
| June 30th | 16 | Cle | Sowers | 1 | 0 | 0 | 2 | 2 | 0 |
| July 12th | 15 | Bal | Guthrie | 1 | 0 | 2 | 2 | 0 | 0 |
| June 29th | 15 | ChC | Ascanio | 8 | 2 | 2 | 2 | 1 | 0 |
| July 8th | 14 | Min | Silva | 3 | 0 | 0 | 2 | 1 | 0 |
| June 17th | 14 | Pit | Salas | 7 | 3 | 2 | 0 | 2 | 0 |
| July 6th | 13 | Min | Cali | 8 | 3 | 2 | 2 | 0 | 0 |
| June 10th | 13 | Det | Robertson | 2 | 3 | 2 | 1 | 0 | 0 |
| July 3rd | 12 | Bal | Cabrera | 4 | 0 | 1 | 2 | 2 | 0 |
| June 5th | 12 | KC | Peralta | 7 | 0 | 0 | 2 | 0 | 0 |
| July 2nd | 11 | Bal | Bedard | 1 | 1 | 0 | 1 | 1 | 0 |
| June 4th | 11 | KC | Hochevar | 4 | 2 | 0 | 1 | 1 | 0 |
| June 26th | 10 | TB | Shields | 5 | 1 | 0 | 2 | 0 | 0 |
| May 26th | 10 | Cle | Byrd | 6 | 0 | 0 | 1 | 0 | 0 |
| June 18th | 9 | Fla | Johnson | 4 | 1 | 0 | 1 | 2 | 0 |
| May 21st | 9 | Cle | Breslow | 7 | 3 | 1 | 2 | 0 | 0 |
| June 4th | 8 | NYY | Villone | 4 | 2 | 0 | 1 | 1 | 0 |
| May 20th | 8 | Cle | Sabathia | 2 | 0 | 0 | 0 | 0 | 0 |
| June 3rd | 7 | Tor | Marcum | 3 | 1 | 0 | 1 | 1 | 0 |
| May 9th | 7 | Sea | Silva | 7 | 3 | 2 | 2 | 0 | 0 |
| May 22nd | 6 | Oak | Lewis | 4 | 0 | 0 | 1 | 2 | 0 |
| April 24th | 6 | NYY | Hawkins | 5 | 2 | 1 | 1 | 0 | 0 |
| April 18th | 5 | Tex | Benoit | 7 | 1 | 1 | 1 | 0 | 0 |
| April 20th | 5 | TB | Jackson | 1 | 2 | 2 | 2 | 0 | 0 |
| April 18th | 4 | Tex | Millwood | 3 | 0 | 0 | 1 | 0 | 0 |
| April 18th | 4 | TB | Niemann | 3 | 3 | 2 | 1 | 2 | 0 |
| April 17th | 3 | Tex | Tejeda | 4 | 0 | 1 | 0 | 0 | 0 |
| April 16th | 3 | Bal | Loewen | 1 | 1 | 2 | 0 | 2 | 0 |
| April 9th | 2 | Oak | Harden | 4 | 3 | 0 | 0 | 0 | 0 |
| March 31st | 2 | Cle | Sabathia | 3 | 3 | 2 | 1 | 1 | 0 |
| April 4th | 1 | Cle | Westbrook | 1 | 0 | 0 | 0 | 2 | 0 |
| March 31st | 1 | Cle | Sabathia | 1 | 2 | 2 | 1 | 1 | 0 |